Nhau

Muna 1968, Kruger-Theimer akaratidza kuti mamodheru emishonga anogona kushandiswa sei kugadzira nzira dzinoshanda dzekurapa. Iyi nzira yekurapa yeBolus, Elimination, Transfer (BET) ine:

dose yebolus yakaverengerwa kuzadza chikamu chepakati (cheropa),

kuisirwa kwemushonga nguva dzose kwakaenzana nechiyero chekubviswa kwemushonga,

kuisirwa kunotsiva kutamiswa kwemasero kuenda kunhengo dzemuviri: [kuderera kwehuwandu hwemasero]

Tsika yechivanhu yaisanganisira kuverenga nzira yekuisira propofol uchishandisa nzira yaRoberts. Muyero we1.5 mg/kg wekutakura unoteverwa nekuisira 10 mg/kg/awa iyo inoderedzwa kusvika pa8 ne6 mg/kg/awa panguva imwe chete yemaminitsi gumi.

Kutarisa nzvimbo zvine chekuita nemhedzisiro

Mhedzisiro huru yemushonga wekurwadziwaMishonga inopinzwa mutsinga ndiyo inonyaradza uye inonyaradza uropi uye nzvimbo iyo mushonga unoita izvi, inonzi nzvimbo yemhedzisiro iuropi. Zvinosuwisa kuti hazvigoneke mukurapa kuyera huwandu hweuropi [nzvimbo yemhedzisiro]. Kunyangwe dai taigona kuyera huwandu hweuropi zvakananga, zvaizodikanwa kuziva huwandu chaihwo hwenzvimbo kana kunyange huwandu hwereceptor apo mushonga unoita zvawo.

Kuwana huwandu hwepropofol hunogara huripo

Dhayagiramu iri pazasi inoratidza mwero wekuisirwa kwepropofol mumuviri unodiwa nekukurumidza mushure mekutorwa mushonga webolus kuitira kuti huwandu hwepropofol muropa hurambe hwakagadzikana. Inoratidzawo kunonoka pakati pehuwandu hweropa nepanzvimbo yemhedzisiro.